(87)Thiourea-derivatives of Fatty Acid

Synthesis and biological activity of fatty acid derivatives of quinine.

Derivatives of quinine with fatty acids including polyunsaturated fatty acids were prepared. They showed moderate antimalarial activity as compared with quinine itself using Plasmodium falciparum. The activities were not dependent on whether the fatty acyl group was saturated or unsaturated. On the other hand, the derivatives showed significantly higher cytotoxicity against a mammary tumor cell...

Cyclopropane Fatty Acid Derivatives: Biosynthesis, Function and Total Synthesis

INTRODUCTION Cyclopropane-containing natural products are very unique owing to their unusual bonding and inherent ring strain (27.5 kcal/mol). 1 This strained ring has been found in naturally occurring terpenes, steroids, amino acids, fatty acids, alkaloids, and nucleic acids. For example, chrysanthemic acid derivatives, produced in plants via isoprenoid pathway are precursors to potent insecti...

Prostaglandin-like fatty acid derivatives from Artemisia anomala.

Four prostaglandin-like fatty acid derivatives anomalone A-D (1-4) were isolated from the aerial part of Artemisia anomala S. Moore. Their structures were determined on the basis of extensive spectroscopic analyses.

Eicosanoids are a group of oxygenated fatty-acid derivatives formed from C20 polyunsaturated fatty acids

derivatives of C20 polyunsaturated fatty acids (PUFAs). Two main pathways are involved in the production of eicosanoids. The lipoxygenase (LO) pathway transforms PUFAs into lipoxins, leukotrienes and monohydroxy fatty acids, whereas the cyclo-oxygenase pathway produces prostaglandins and thromboxanes. These pathways predominantly use two PUFAs, arachidonic acid (AA, 20:4n-6) and eicosapentaenoi...

Fatty Acid Profles of Ram's Sperm after Removing Some Fatty Acid Sources from the Diets and Persistency of Fatty Acids in Sperm